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The Effect of Oat Cream on skin reaction caused by radiotherapy.

The assessment of Avena Sativa cream efficacy on skin reactions caused by radiotherapy in patients with breast cancer.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201311015987N8
Enrollment
60
Registered
2014-08-05
Start date
2014-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer. Malignant Neoplasm of Breast

Interventions

Intervention 1: At the first time of beginning radiotherapy we will recommend to patients use the cream which prepared from oat extract, three times a day each 8 hours daily (TDS), in the radiotherap
Treatment - Drugs
Placebo
At the first time of beginning radiotherapy we will recommend to patients use the cream which prepared from oat extract, three times a day each 8 hours daily (TDS), in the radiotherapy area, amount o
In the control group patients will use placebo (extract-free cream base).

Sponsors

Tehran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: Women with breast cancer; Without any skin lesion. Exclusion criteria: Patients with uncontrolled diabetes; Acquired immunodeficiency syndrome; A history of allergy to medicinal plants.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The grade of skin reaction caused by radioytherapy. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher-made questionnaire.;Erythema. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher-made questionnaire.;Dry desquamation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Using the RTOG questionnaire and researcher-made questionnaire.;Itching. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient and using a researcher-made questionnaire.;Burning sensation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Ask the patient and using a researcher-made questionnaire.;Changes in daily activities. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy a

Secondary

MeasureTime frame
Patchy and Distribution Moist Desquamation. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Examination by a physician.;Drainage, Infection, Cellulitis. Timepoint: At the intervals of 10 days after initiation of treatment , 28 days after initiation of treatment, on the last day of radiotherapy and after that in two times with one week interval, after the end of radiotherapy participants will be followed up. Method of measurement: Examination by a physician.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahrzad ghiyasvandiyan

Tehran University of Medical Sciences,School of Nursing and Midwifery

shghiyas@tums.ac.ir+98 21 6642 0739

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026