Skip to content

Comparative efficacy of oral Gabapantine, local Bupivacaine and Pethidine injections in reducing pain after tonsillectomy

Comarative efficacy of oral Gabapentine, local Bupivacaine and intravenous Pethidine on postoperative pain after tonsillectomy, in Shahrekord Kashani hospital operative room.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201310296252N4
Enrollment
105
Registered
2014-01-03
Start date
2007-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sore throat. Pain in throat and chest

Interventions

Intervention 1: In first group 600 mg oral Gabapantine was administered 1 hour before anesthesia. Intervention 2: In second group 2 ml Bupivacaine 0.25% was injected by surgeon in tonsillar bed after
Treatment - Drugs
In first group 600 mg oral Gabapantine was administered 1 hour before anesthesia.
In second group 2 ml Bupivacaine 0.25% was injected by surgeon in tonsillar bed after tonsillectomy.
In third group 1 mg/kg pethidiine was injected intravenous after intubation.

Sponsors

Shahrekord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 17 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:The 7-17years old patients candidats tonsillectomy that were in ASA I,III class anesthsia according anesthesia society of USA. Exclusion criteria: Severe anxiety before surgery; upper respiratory tract infection; having speasial disease; use special drugs; exessive bleeding during surgery; repeated anesthesia.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain after surgery. Timepoint: After enterance to recovery,3,6,12,24hours after surgery. Method of measurement: Mc-Gill questionnaire.

Secondary

MeasureTime frame
Blood presure. Timepoint: Every 10 minutes until entering to ward. Method of measurement: with manometer.;Heart rate. Timepoint: Every 10 minutes until entering to ward. Method of measurement: With puls oxymeter.;Vomiting. Timepoint: During 24 hours after surgery. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoroush Amani MD

Shahrekord University of Medical Sciences

info@Skums.ac.ir+98 38 1333 0061

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026