Effect of wheat germ juice on premenstural syndrome

Evaluation the effect of wheat germ extract capsules on the severity of Premenstural symptomes in women employed in hospitals in Hamadan

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201310286807N8

Enrollment

Registered

2013-12-21

Start date

2013-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pre menstural syndrome. Premenstrual tension syndrome

Interventions

Intervention 1: Intervention group: wheat germ extract, capsules, 400 mg orally, three times a day for two months. Intervention 2: Control group: Starch, Capsule 400 mg orally three times a day for tw

Treatment - Drugs

Intervention group: wheat germ extract, capsules, 400 mg orally, three times a day for two months

Control group: Starch, Capsule 400 mg orally three times a day for two consecutive months

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age should be between 20 and 45 years; BMI should be between 19/8 and 26; they should be non smokers; they should have 3 to 10 days bleeding in two months prior to study; Regular menstrual cycles should be 21-35 days; premenstural syndrome based on premenstural syndrome provisional diagnosis questionnaire and daily form showing premenstural syndrome symptoms after 2 months should be proved; they should have no known mental illnesses; they should have no physical illnesses such as diabetes, seizure disorders, hypothyroidism and so on; There should be no death of close relatives; divorce or other adverse events in the last 3 months; Surgery should not be performed in the three months before entering study; Antidepressants, hormonal contraceptives, medroxy progesterone acetate, and vitamins should not be taken in the past three months; Exclusion criteria: pregnancy; incidents like the death of close relatives, divorce, and other adverse events; taking 3 capsules of wheat germ or less on two consecutive days; taking supplements; eating wheat germ.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of pre menstural syndrome. Timepoint: 8 weeks Before treatment, 8 weeks after treatment. Method of measurement: Diagnostic and Statistical Manual of Mental Disorders, 4th. Edition.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeddighe Amir Ali Akbari

Shahid Beheshti University of Medical Sciences

asa_akbari@yahoo.com+98 21 8820 2512

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026