Effect of citrus aurantium and citrus aurantifolia on endothelial function

Effect of citrus aurantium and citrus aurantifolia on endothelial function among overweight children and adolescents aged 9-18

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013102715190N1

Enrollment

Registered

2013-12-07

Start date

2013-11-17

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

overweight and obesity. Obesity due to excess calories

Interventions

Intervention 1: placebo (corn starch) as similar appearance capsules (1 capsule/12 hour) for control group. Intervention 2: citrus aurantium capsules (1 capsule/12 hour) for intervention group 1. Int

Treatment - Drugs

placebo (corn starch) as similar appearance capsules (1 capsule/12 hour) for control group

citrus aurantium capsules (1 capsule/12 hour) for intervention group 1

citrus aurantifolia capsules (1 capsule/12 hour) for intervention group 2

Eligibility

Sex/Gender

All

Age

9 Years to 18 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age (9-18 years); body mass index (BMI) above 85th centile for age and sex; no hypothyroidism. Exclusion criteria: medical therapy for dyslipidemia; smoking or exposure to tobacco.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Flow-mediated dilation (FMD). Timepoint: baseline and at the end of the study (after 1 month intervention). Method of measurement: high-resolution B-mode sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Khosravi

Isfahan University of Medical Sciences

ELHAMKHOSRAVI 1389@YAHOO.COM+98 31 1222 2127

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026