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Evaluation of the effect of Microrelin in treatment of metastatic prostate cancer

Evaluation of efficacy of Microrelin in reducing levels of PSA and Testosterone in patients with metastatic prostate cancer

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201310229819N3
Enrollment
40
Registered
2014-01-20
Start date
2014-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate Cancer. Malignant neoplasm of prostate

Interventions

Microrelin 3.75 milligram (Triptorelin which is LHRH agonist) each 28 days intramuscular Produced by, PREMM Company of Italy Imported by, Pooyesh Darou Company.
Treatment - Drugs
Microrelin 3.75 milligram (Triptorelin which is LHRH agonist) each 28 days intramuscular Produced by, PREMM Company of Italy Imported by, Pooyesh Darou Company

Sponsors

Vice chancellor for research Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Inclusion criteria: All patients with metastatic prostate cancer without age limitation who are referred to urology clinic of Imam Khomeyni Hospital in 01.21.2014 until 01.21.2015 and accepted the term and condition of this study. Exclusion criteria: Reluctance of patients to continue the study or in case of death

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
PSA. Timepoint: Before intervention, one month after intervention, three months after intervention and six months after intervention. Method of measurement: ELIZA.;Serum Testosterone. Timepoint: Before intervention, one month after intervention, three months after intervention and six months after intervention. Method of measurement: ELIZA.

Secondary

MeasureTime frame
Loss of libido (Sexual desire was absent in all cases following castration) and Hot flash (As a subjective feeling of warmth in the head followed by objective perspiration, hot flashes are not life threatening but are among the most common side effects of androgen ablation). Timepoint: At every visit. Method of measurement: With history taking and physical exam.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYonesian Masud

Vice chancellor for research, Tehran University Of Medical Sciences

Resdeputya@tums.ac.ir+98 21 8898 7381

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026