Comparison of oxygenation and lung mechanics between two types of mechanical ventilation

Comparison of Syncronized Intermittent Mandatory ventilation and Pressure Support Ventilation in oxygenation and lung mechanics in critically ill patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013102215109N1

Enrollment

Registered

2015-08-16

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory failure that needs mechanical ventilation. Respiratory failure, unspecified

Interventions

Intervention 1: Synchronized intermittent mechanical ventilation. Intervention 2: pressure support ventilation.

Treatment - Other

Synchronized intermittent mechanical ventilation

pressure support ventilation

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: need to mechanical ventilation more than 1 week; age between 20-50 years old; normal pulmonary mechanic(C>50 and R<10) Exclusion criteria:patient who death before 48 hours of admission in ICU; History of asthma, COPD, bronchectasis, and other pulmonary disease; history of liver, brain, heart and kidney disease; inadequate spontaneous breathing; refuse of patient

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Given Oxygen volume. Timepoint: every day for six days. Method of measurement: Manumeter.;Compliance. Timepoint: every day for six days. Method of measurement: Spirometer.;Pulmonery end expiratory pressure. Timepoint: every day for six days. Method of measurement: Ventilator.;100 mili second pressure. Timepoint: every day for six days. Method of measurement: pressure gauge.	—

Secondary

Measure	Time frame
Pneumonia. Timepoint: every 3 days for six days. Method of measurement: Symptoms and lung CT scan.;Symptoms and imaging of acute respiratory distress syndrome. Timepoint: every 3 days for six days. Method of measurement: History taking and lung CT scan.;Symptoms of Ventilator related injury. Timepoint: every 3 days for six days. Method of measurement: History taking.;Cardiac output. Timepoint: every day for six days. Method of measurement: Echocardiography.;Asynchrony. Timepoint: every day for six days. Method of measurement: Symptoms.	—

Measure

Time frame

Pneumonia. Timepoint: every 3 days for six days. Method of measurement: Symptoms and lung CT scan.;Symptoms and imaging of acute respiratory distress syndrome. Timepoint: every 3 days for six days. Method of measurement: History taking and lung CT scan.;Symptoms of Ventilator related injury. Timepoint: every 3 days for six days. Method of measurement: History taking.;Cardiac output. Timepoint: every day for six days. Method of measurement: Echocardiography.;Asynchrony. Timepoint: every day for six days. Method of measurement: Symptoms.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfarin Zamani

Tehran University of Medical Sciences

mitra_az63@yahoo.com+98 21 6604 3044

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026