Effect of probiotic yogurt fortified with vitamin D on fatty liver

Effects of probiotic yogurt fortified with vitamin D in comparison to conventional yogurt on hepatic enzymes, lipid profile, glycemic and anthropometric indices in patients with non-alcoholic fatty liver disease

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20131022015111N3

Enrollment

Registered

2018-02-18

Start date

2017-10-23

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fatty liver. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: Intervention group: Riched yogurt (100 cc/day) with 1000 IU vitamin D and 40000000 cfu Probiotic. Intervention 2: Control group: Plain yogurt (100 cc/day) receiving group.

Eligibility

Sex/Gender

All

Age

25 Years to 55 Years

Inclusion criteria

Inclusion criteria: individuals with new diagnosed fatty liver disease individuals with grade 1 or 2 fatty liver disease individuals with the age of 25 to 55 years old individuals who have full satisfaction to participate

Exclusion criteria

Exclusion criteria: individuals who use any kind of drug individuals who has allergic to yogurt individuals who are suffering from other chronic diseases like: cardio vascular diseases, kidney diseases, thyroid and... individuals who are suffering from other chronic diseases like: any kind of hepatitis, cirrhosis and ... or had liver transplant. individuals who had a background of cancer women who use contraceptive drugs individuals who use certain regimens or weight loss regimens. individuals who use any vitamin supplements individuals who use any kind of probiotic supplement or probiotic food products individuals who take any antioxidant supplements individuals who have taken any type of fiber supplement or omega-3 supplement during 6 weeks before starting the study. individuals who have taken antibiotics over the 2 weeks before starting the study. Women who are pregnant, lactating or menopause. individuals who use cigarettes and alcohol.

Design outcomes

Primary

Measure	Time frame
Alanine Aminotransferase. Timepoint: Before and 3 month after intervention. Method of measurement: by using Kit.;Aspartate Aminotransferase. Timepoint: Before and 3 month after intervention. Method of measurement: by using Kit.;Total Cholesterol. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Trigliceride. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Low-density lipoprotein. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;High-density lipoprotein. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Fast Blood Sugar. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Serum Insulin. Timepoint: Before and 3 month after intervention. Method of measurement: Insulin MONOBIND Kit.;Weight. Timepoint: Before and 3 month after intervention. Method of measurement: scale.;Abdomen Circumference. Timepoint: Before and 3 month after intervention. Method of measurement: Tape measure.;Hip Circumference. Timepoint: Before and 3 month after intervention. Method of measurement: Tape measure.;Body Fat Percentage. Timepoint: Before and 3 month after intervention. Method of measurement: Body Analyzer Machine.;Body Muscle Percentage. Timepoint: Before and 3 month after intervention. Method of measurement: Body Analyzer Machine.;Vitamin D. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.	—

Measure

Time frame

Alanine Aminotransferase. Timepoint: Before and 3 month after intervention. Method of measurement: by using Kit.;Aspartate Aminotransferase. Timepoint: Before and 3 month after intervention. Method of measurement: by using Kit.;Total Cholesterol. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Trigliceride. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Low-density lipoprotein. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;High-density lipoprotein. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Fast Blood Sugar. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.;Serum Insulin. Timepoint: Before and 3 month after intervention. Method of measurement: Insulin MONOBIND Kit.;Weight. Timepoint: Before and 3 month after intervention. Method of measurement: scale.;Abdomen Circumference. Timepoint: Before and 3 month after intervention. Method of measurement: Tape measure.;Hip Circumference. Timepoint: Before and 3 month after intervention. Method of measurement: Tape measure.;Body Fat Percentage. Timepoint: Before and 3 month after intervention. Method of measurement: Body Analyzer Machine.;Body Muscle Percentage. Timepoint: Before and 3 month after intervention. Method of measurement: Body Analyzer Machine.;Vitamin D. Timepoint: Before and 3 month after intervention. Method of measurement: By using Kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojgan Morvaridzadeh

Kermanshah University of Medical Sciences

morvaridzadehm@yahoo.com+98 83 3723 3221

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026