The effect of paracetamol on post operative pain, nausea and vomiting after strabismus surgery

Evaluation the effect of intravenous paracetamol on post operative pain and nausea and vomiting in pediatric patients undergoing strabismus surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201310218768N2

Enrollment

120

Registered

2014-05-20

Start date

2013-12-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: acute postoperative pain. Condition 2: nausea and vomiting. Acute pain Nausea and vomiting

Interventions

Intervention 1: control group: Intravenous infusion of normal saline(1.5ml/kg) in 20 minutes at the end of surgery. Two or more vomiting episodes will be treated with ondansetrone 0. 1mg/kg. The Faci

Treatment - Drugs

control group: Intravenous infusion of normal saline(1.5ml/kg) in 20 minutes at the end of surgery. Two or more vomiting episodes will be treated with ondansetrone 0. 1mg/kg. The Facial Pain Scale wi

Intervention group: Intravenous infusion of paracetamol 15mg/kg (1.5ml/kg of 1 gram paracetamol in 100 cc normal saline) in 20 minutes at the end of surgery. Two or more vomiting episodes will be tr

Eligibility

Sex/Gender

All

Age

2 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children aged between 2 and 14 years, ASA physical status I and II scheduled for strabismus surgery under general anaesthesia Exclusion criteria: Those with hepatic or renal failure, known allergy to study drugs, those with a history of previous PONV or motion sickness, using antihistamine or antiemetic drugs or steroids in previous 24 hours before surgery,

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Nausea and vomiting. Timepoint: In recovery, 6 hours after surgery, 12 hours after surgery, 24 hours after surgery. Method of measurement: Questionare.;Pain score. Timepoint: In recovery, 6 hours after surgery, 12 hours after surgery, 24 hours after surgery. Method of measurement: Facial pain scale.	—

Secondary

Measure	Time frame
Rescue analgesic dose. Timepoint: After 24 hours. Method of measurement: Questionare.;Rescue ondansetrone dose. Timepoint: 24 hours after surgery. Method of measurement: Questionare.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahshid Nkooseresht M.D

Hamadan University of Medical Sciences

nikooseresht@umsha.ac.ir+98 81 1264 0049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026