Effect of a lowering blood glucose drug on protein loss with urine in patient with kidney disease due to diabet

Effect of Pioglitazone on proteinuria, inflammatory and oxidative markers in patient with diabetic nephropathy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013102115105N1

Enrollment

Registered

2014-03-12

Start date

2014-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic nephropathy. Diabetes mellitus With renal complications

Interventions

Tablet Pioglitazone, 30 miligram, pathway oeal, daily.

Treatment - Drugs

Tablet Pioglitazone, 30 miligram, pathway oeal, daily

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (The patient with Diabetic nephropathy with Diabet type2; Glomerular filtration rate equal or greater than 30; Age graeter 18 & smaller 65 years old; Agreement to participate in the study) Exclusion criteria: (Glomerular Filtration Rate smaller than 30; Dyspnea; CHF; Liver failure; General edema; Age smaller than 18 & greater than 65 years old; Body Mass Index equal or greater than 40

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Proteinuria. Timepoint: Monthly. Method of measurement: 24 urin and according to miligram per deciliter.	—

Secondary

Measure	Time frame
Ferritin. Timepoint: Monthly. Method of measurement: Elisa and according to Nanogram per mililiter.;High sensitivity C- Reactive protein. Timepoint: Monthly. Method of measurement: Elisa according to Nanogram per mililiter.;Malondialdehyde. Timepoint: Monthly. Method of measurement: Elisa and according to micromol per liter.;Total antioxidant. Timepoint: Monthly. Method of measurement: Elisa and according to microgram per mililiter.	—

Measure

Time frame

Ferritin. Timepoint: Monthly. Method of measurement: Elisa and according to Nanogram per mililiter.;High sensitivity C- Reactive protein. Timepoint: Monthly. Method of measurement: Elisa according to Nanogram per mililiter.;Malondialdehyde. Timepoint: Monthly. Method of measurement: Elisa and according to micromol per liter.;Total antioxidant. Timepoint: Monthly. Method of measurement: Elisa and according to microgram per mililiter.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarahnooosh Farnood

Tabriz University of Medical Sciences

Farnood_farahnosh@yahoo.com+98 41 1337 3966

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026