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The effect of an herbal extract (Arnebia euchroma) for wound healing

The Comparison of the effect of hydroalcoholic extract gel of Arnebia euchroma and Silver Sulfadiazin and Alpha ointments on wound healing in patients with heat-induced superficial skin wounds

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013102115102N1
Enrollment
300
Registered
2014-02-11
Start date
2014-01-03
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: heat-induced Skin wounds. Condition 2: heat-induced skin wounds. Condition 3: Heat-induced skin wounds. Burn of first degree, body region unspecified Burn of second degree, body region unspecified Burns involving less than 10% of body surface

Interventions

Intervention 1: Group E5: patients were treated with Arnebia euchroma gel 20% twice daily for 28 days. The gel covered the wound properly then dressed with bandages in the standard method. Interventio
Treatment - Drugs
Group E1: patients are treated with Silver sulfadiazine ointment twice daily for 28 days. The ointment covere the wound properly then dresse with bandages in the standard method.
Group E2: patients are treated with Alpha ointment twice daily for 28 days. The ointment covere the wound properly then dress with bandages in the standard method.
Group P1: patients are treated with Arnebia euchroma gel 5% twice daily for 28 days. The gel cover the wound properly then dress with bandages in the standard method.
Group E5: patients were treated with Arnebia euchroma gel 20% twice daily for 28 days. The gel covered the wound properly then dressed with bandages in the standard method.
Group E3: patients are treated with Arnebia euchroma gel 5% twice daily for 28 days. The gel covere the wound properly then dresse with bandages in the standard method.
Group P3: patients are treated with Arnebia euchroma gel 20% twice daily for 28 days. The gel covere the wound properly then dresse with bandages in the standard method.
Group E4: patients are treated with Arnebia euchroma gel 10% twice daily for 28 days. The gel covere the wound properly then dresse with bandages in the standard method.
Group P2: patients are treated with Arnebia euchroma gel 10% twice daily for 28 days. The gel covere the wound properly then dresse with bandages in the standard method

Sponsors

SadraTech Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: Having wounds with 2cm area or less; Having no other systemic diseases affecting the wound healing process; Having no other dermatological diseases; Filling informed consent and participating in using the prescribed drugs; Having wounds caused by traumatic injuries or burns Exclusion criteria:Having wounds sized more than 2 cm; Having any systemic diseases or dermatological diseases; Willing to leave the study at any time during the treatment; Having wounds caused by any other reasons than traumatic injury or burns

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound closure rate. Timepoint: at the begining of the study and then daily till the closure of the wound. Method of measurement: ruler.

Secondary

MeasureTime frame
Scar formation. Timepoint: at the end. Method of measurement: observation.;Wound infection. Timepoint: during and at the end of the study. Method of measurement: Culture.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoheil Ashkani Esfahani

Shiraz University of Medical Sciences

soashkani@gmail.com+98 917 339 7040

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026