Breast cancer. Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention 1: Intervention group: Curcumin along with standard regime will be assigned to intervention group. The daily dose of crocin will be 80 mg during 24 weeks. Intervention 2: Control group:
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with metastatic breast cancer that is measurable Breast cancer patients who have not received any chemotherapy for metastasis patients at the age of 25 to 70
Exclusion criteria
Exclusion criteria: History of any allergy to turmeric or its products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival. Timepoint: One year after the treatment is completed. Method of measurement: Patient follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-free survival. Timepoint: During treatment and after it every 3 months. Method of measurement: criteria of Response evaluation criteria in solid tumors.;Anemia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Neutropenia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Thrombocytopenia. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of complete blood count.;Kidney function. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of BUN and creatinine.;Liver function. Timepoint: Before each session of monthly chemotherapy. Method of measurement: laboratory assessment of SGOT and SGPT. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSoodabeh Shahidsales
Mashhad University of Medical Sciences
Outcome results
None listed