Skip to content

The effect of combination use of pentoxifylline and L-carnitine on sperm-analysis of Idiopathic Oligoasthenoteratozoospermia patients

The effect of combination use of pentoxifylline and L-carnitine on Idiopathic Oligoasthenoteratozoospermia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201310131981N3
Enrollment
212
Registered
2014-07-21
Start date
2012-04-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male infertility. male infertility

Interventions

Intervention 1: The intervention group one consumed orally 400 mg pentoxifylline and 400 mg L-carnitin twice daily for 3 months. Intervention 2: The intervention group two consumed orally400mg pe
Treatment - Drugs
The intervention group one consumed orally 400 mg pentoxifylline and 400 mg L-carnitin twice daily for 3 months
The intervention group two consumed orally400mg pentoxifylline and placebo twice daily for 3 months
The intervention group three consumed orally400mg L-carnitin and placebo twice daily for 3 months
The control group fourth consumed orally two type placeboes twice daily for 3 months

Sponsors

Medical Sciences University of kerman
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :infertile men with Oligoasthenoteratozoospermia;men with age between 25- 40 years old; men without history of medical or surgery for infertility ;men with wives with ages between 20 - 35 years old and or with no known female fertility risk factors . Exclusion criteria:infertile men with Oligoasthenoteratozoospermia with known etiologies.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Spermogram parameters change. Timepoint: after intervention. Method of measurement: spermogram.;Assissted reproductive technic rates. Timepoint: before intervention. Method of measurement: spermogram.

Secondary

MeasureTime frame
Spermogram improving. Timepoint: after 3 months from intervention. Method of measurement: spermogram.;Qualification of Assissted reproductive technic rates. Timepoint: 3 months after intervention. Method of measurement: spermogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Gholamreza Sepehri

Research Center of kerman Medical Sciences University

g_sepehri@kmu.ac.ir+98 34 1226 3857

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026