Effects of local Progesterone injection versus Corticosteroid injection in patients with Carpal Tunnel Syndrome

Study of the effects of local Progesterone injection versus Corticosteroid injection in patients with mild and moderate Carpal Tunnel Syndrome in Physical Medicine and Rehabilitation clinic of Modarres and shohadaie Tajrish Hospitasls from 2012 to 2013

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013101313442N4

Enrollment

Registered

2013-11-01

Start date

2012-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome. Carpal Tunnel Syndrome

Interventions

Intervention 1: Single injection of 1 ml of Triamcinolon with 2cc syringe and Prefabricated hand wrist splint for CTS for 8 weeks. Intervention 2: Single injection of 1 ml 17 Alpha Hydroxiprogesteron

Treatment - Drugs

Single injection of 1 ml of Triamcinolon with 2cc syringe and Prefabricated hand wrist splint for CTS for 8 weeks

Single injection of 1 ml 17 Alpha Hydroxiprogesterone with 2cc syringe and Prefabricated hand wrist splint for CTS for 8 weeks

Eligibility

Sex/Gender

Female

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: patient with mild and moderate CTS confirmed by the presence of 1 or more of the following standard electrophysiological criteria:1- prolonged distal motor latency (DML) (abnormal =4.2 ms)of Median nerve and 2) prolonged antidromic distal sensory latency (DSL) to the third digit (abnormal >3.6 ms; age between 20 to 65 years old. Exclusion criteria:Pregnancy; Severe degree CTS; Background metabolic diseases such as: Diabetes mellitus; Hypothyroidism; Rheumatoid arthritis; Previous history of Corticosteroid injection in Carpal Tunnel; Severe atrophy of Thener muscles; cervical radiculopathy or significant polyneuropathy; Unwillingness to participate in the present study; patient younger than 20 or older than 65 years old.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 0,10 weeks, 6 months. Method of measurement: Visual Analog Scale, that is from 0-10 and zero (0) means that you did not have any pain and ten (10) means that you had the worst pain imaginable.;Functional Status. Timepoint: 0, 6weeks, 6months. Method of measurement: Bostone/levine Functional Status Scale Questionnare.;Symptome Severity(pain and paresthesia). Timepoint: 0,10weeks, 6months. Method of measurement: Bostone/levine Symptome Severity Scale Questionnare.;Distal Sensory Peak Latency(SNAP) of median nerve. Timepoint: 0,10weeks, 6months. Method of measurement: EDX Indexes.;Distal Motor Onset Latency(CMAP) of median nerve. Timepoint: 0,10weeks, 6months. Method of measurement: EDX indexes.	—

Measure

Time frame

Pain. Timepoint: 0,10 weeks, 6 months. Method of measurement: Visual Analog Scale, that is from 0-10 and zero (0) means that you did not have any pain and ten (10) means that you had the worst pain imaginable.;Functional Status. Timepoint: 0, 6weeks, 6months. Method of measurement: Bostone/levine Functional Status Scale Questionnare.;Symptome Severity(pain and paresthesia). Timepoint: 0,10weeks, 6months. Method of measurement: Bostone/levine Symptome Severity Scale Questionnare.;Distal Sensory Peak Latency(SNAP) of median nerve. Timepoint: 0,10weeks, 6months. Method of measurement: EDX Indexes.;Distal Motor Onset Latency(CMAP) of median nerve. Timepoint: 0,10weeks, 6months. Method of measurement: EDX indexes.

—

Secondary

Measure	Time frame
Patient Satisfication after trearment. Timepoint: 0,10weeks, 6months. Method of measurement: Patient statement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShadi Shahraeeni

Modarres Hospital

dr.shahraeeni@gmail.com+98 21 2207 4090

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 15, 2026