Fat Embolism. Fat embolism (traumatic)
Conditions
Interventions
Intervention 1: intraveinously injection of Methyl prednisolone with the dosage of 10 mg/kg every 4 hours during 72 h of addmission. Intervention 2: intraveinously injection of placebo(normal
Treatment - Drugs
Placebo
intraveinously injection of Methyl prednisolone with the dosage of 10 mg/kg every 4 hours during 72 h of addmission
intraveinously injection of placebo(normal salin) with the dosage of 10 mg/kg every 4 hours during 72 h of addmission
Sponsors
Research and Technology Department of Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patiens with closed fractures of femor or tibia that refers to poursina hospital Exclusion criteria: patients with skull,chest,lungs,pelvic,diaphragm,urogential injuries and pathologic fracture,pregnant women, history of cardiac and lung disease or a history of corticosteroid treatment will not be included in
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pco2>55mmhg. Timepoint: first visit,12h.24h,72h after admission. Method of measurement: mmhg, lab tests.;Po235 per minute. Timepoint: first visit,12h.24h,72h after admission. Method of measurement: clinical examination.;Dyspnea, Tachypnea. Timepoint: first visit,12h.24h,72h after admission. Method of measurement: clinical examination. | — |
Secondary
| Measure | Time frame |
|---|---|
| Acidotic Arterial blood PH. Timepoint: first visit, 12h,24,72 h after admission. Method of measurement: Lab test(ABG). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Sadeq Mousavi
Research and Technology Department, Guilan University of Medical Sciences
Outcome results
None listed