The effect of local cooling on pain related to root canal therapy

The effect of local cooling on pain during injection, root canal therapy, and after treatment in mandibular molars with irreversible pulpitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013101214985N1

Enrollment

100

Registered

2014-01-31

Start date

2013-11-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irreversible pulpitis of first or second mandibular molars. ????????? ???? ? ??? ??????

Interventions

Intervention 1: Inferior alveolar nerve block after cooling of the skin over the injection site. Intervention 2: Inferior alveolar nerve block without cooling of the skin over the injection site.

Treatment - Other

Inferior alveolar nerve block after cooling of the skin over the injection site

Inferior alveolar nerve block without cooling of the skin over the injection site

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Persons without systemic diseases with minimum age of 18 years old; having first or second mandibular molar tooth diagnosed with irreversible pulpitis; normal periapical radiographic appearance; without percussion sensitivity; having no pain before treatment; absence of taking medication within 6 hours before treatment. Exclusion criteria: Presence of sensitivity to lidocaine with 1:80,000 epinephrine; presence of periodontal ligament widening; pregnancy or lactation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain degree. Timepoint: During needle insertion. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: During injection. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: During treatment. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: At times 6, 12, 24, 36, 48 and 72 hours after treatment. Method of measurement: Visual Analogous Scale (VAS).	—

Measure

Time frame

Pain degree. Timepoint: During needle insertion. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: During injection. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: During treatment. Method of measurement: Visual Analogous Scale (VAS).;Pain degree. Timepoint: At times 6, 12, 24, 36, 48 and 72 hours after treatment. Method of measurement: Visual Analogous Scale (VAS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiamak Samanipoor

Kerman University of Medical Sciences

s_samanipoor@yahoo.com+98 34 1247 7388

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026