Autism Spectrum Disorder. Autistic disorder
Conditions
Interventions
In this study, children with autism will be treated with a ketogenic diet. The classic ketogenic diet is high in fat, low in carbohydrates, and moderate in protein, adjusted to a ratio of 4:1 or 3:1 (
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Years to 10 Years
Inclusion criteria
Inclusion criteria: Age 3 to 10 years The complaint of speech delay and lack of social communication according to the points obtained: 20-8 with high risk of autism, 3-7 with moderate risk for autism in the completed Modified Checklist for Autism in Toddlers (M-CHAT) questionnaire. The child's parents or caregivers have the appropriate training to start, continue the diet, measure urine ketones, and record information in the relevant form, and the informed consent of the patient's parents for the child's participation in the study; is.
Exclusion criteria
Exclusion criteria: History of clinical seizures in history Presence of epileptiform waves in EEG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of cognitive function. Timepoint: Before starting the diet and 3 months later. Method of measurement: Evaluation and comparison of Autism Treatment Evaluation Checklist (ATEC) score in children with autism before and after the diet. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation and comparison of beta-hydroxybutyrate levels. Timepoint: Before starting the diet and 3 months later. Method of measurement: Serum levels of beta-hydroxybutyrate before and after applying the ketogenic diet will be assessed by a biochemistry autoanalyzer and a commercial kit using a photometric method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mohammad Barzegar
Tabriz University of Medical Sciences
Outcome results
None listed