Partial thickness burning. Burn of first degree of shoulder and upper limb, except wrist and hand
Conditions
Interventions
Intervention 1: Intervention group: using topical solution derived from Centella asiatica. Intervention 2: Control group: treatment with Silver Sulfadiazine 1%.
Treatment - Drugs
Intervention group: using topical solution derived from Centella asiatica
Control group: treatment with Silver Sulfadiazine 1%
Sponsors
Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
14 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: every partial thickness burning with less than 10% involved body and being in limbs; time of burning less than 48 hours; No other injury except of burning lesion and have general health body; age between 14 to 60 years Exclusion criteria: Existence of every cerebro-vascular diseases; cardiovascular diseases; endocrine diseases; liver diseases; renal diseases; history of abuse in alcohol or drugs; using antibiotic (oral or parenteral) at the same time; steroid or other immunosuppressive drug; burning due to lightning arresting; electrical instruments ; local burning of hand
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective symptoms. Timepoint: Day 2,7 and 14 after initiating treatment. Method of measurement: It will be scored by below symptoms: dryness: 1=yes, 0=no; itching: 1=yes, 0=no; irritation: 1=yes, 0=no.;Objective symptoms. Timepoint: Day 2,7 and 14 after initiating treatment. Method of measurement: It will be scored by below symptoms: Flexibility: 0=no, soft=1, yielding=2, stiff=3, sticky=4; Height: normal=0, 1-2mm=1, 3-4mm= 2, 5-6mm=3, >6mm=4; Vasculature: normal=0, pinky=1, red= 2, amethystine=3; Pigmentation: normal=0, mild=1, moderate=2, severe=3/ 0-4= lack of objective symptoms, 4-8= mild, 8-12= moderate, 12-14= severe.;Surface of burning. Timepoint: Day 2,7 and 14 after initiating treatment. Method of measurement: By evaluation of morphometric features with image analyzer software.;Severity of pain. Timepoint: Day 2,7 and 14 after initiating treatment. Method of measurement: By using Visual Analogue Score (VAS).;Added at 2015-10-02: re-epithelialization. Timepoint: Added at 2015-10-02: from day o to complete of re-epithelialization. Method of measurement: Added at 2015-10-02: examination and observation with surgeon and sub-specialist of burning.;Added at 2015-10-02: Complete Healing. Timepoint: Added at 2015-10-02: from day o to complete of complete healing of scar. Method of measurement: Added at 2015-10-02: examination and observation with surgeon and sub-specialist of burning. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmin Saeidinia
Guilan University of Medical Sciences
Outcome results
None listed