Evaluate the performance of three different diets (low calorie, balanced, low calorie - low carb and low calories - low fat) on high-sensitivity c-reactive protein and lipid profile in overweight individuals

Evaluate the performance of three different diets (low calorie, balanced, low calorie - low carb and low calories - low fat) on high-sensitivity c-reactive protein and lipid profile in overweight adults aged 25-60 years

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013100614914N1

Enrollment

120

Registered

2014-09-09

Start date

2014-03-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight. Overweight

Interventions

Intervention 1: group A: low calorie-balanced:50-55% carbohydrate,12-15% protein,25-30% fat,500 kcal less than the daily intake for a period of three months from baseline. Intervention 2: group B: low

Lifestyle

group A: low calorie-balanced:50-55% carbohydrate,12-15% protein,25-30% fat,500 kcal less than the daily intake for a period of three months from baseline

group B: low calorie-low carbohydrate:35-40% carbohydrate,25-30% protein,<40% fat,500 kcal less than the daily intake for a period of three months from baseline

group C: low calorie-balanced:45-60% carbohydrate,15-20% protein,<20% fat,500 kcal less than the daily intake for a period of three months from baseline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Individuals must complete a consent form to participate in the project; a certificate of age from 25 to 60 years; no use of lipid-lowering medications; no history of kidney disease; liver disease; heart disease; thyroid disorders, diabetes; and rheumatologic diseases. Exclusion criteria: those who did not fill out a consent form or were withdrawn from the plan; Changes in diet; changes in daily physical activity; pregnancy; lactation or use of oral contraceptives; Conditions that require patients to lipid-lowering drugs; Alcohol consumption; Non-fasting blood samples; Hospitalization; time of sampling; Acute infectious diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
High-sensitivity c-reactive protein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Serum triglycerides. Timepoint: Before the experiment,12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;High-density lipoprotein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Low-density lipoprotein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Total cholesterol. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.	—

Measure

Time frame

High-sensitivity c-reactive protein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Serum triglycerides. Timepoint: Before the experiment,12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;High-density lipoprotein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Low-density lipoprotein. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.;Total cholesterol. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: biochemical measurements on blood sample.

—

Secondary

Measure	Time frame
Body Mass Index. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: Calculated according to the formula.;Weight. Timepoint: Before the experiment, 12 weeks after the intervention. Method of measurement: Electronic Scales.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahdad Khosropanah

Shiraz University of Medical Sciences

shahdad44@yahoo.com+98 71 1229 7767

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026