Femoral fracture. Fracture of femur
Conditions
Interventions
Intervention 1: Injection of 15 mg/kg intravenous tranexamic 5 min before skin incision in intervention group. Intervention 2: Injection of 15 mg/kg intravenous normal sailine 5 min before skin incis
Treatment - Drugs
Injection of 15 mg/kg intravenous tranexamic 5 min before skin incision in intervention group.
Injection of 15 mg/kg intravenous normal sailine 5 min before skin incision in control group.
Sponsors
Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: writing consent, age 18-65, ASA class 1-2. exclusion criteria:history of coagulopathy, thrombosis, aspirin use or other antiplatelete drugs during 2 weeks prior to the surgery, NSAID use 2 days before surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding. Timepoint: During surgery till 48 hours after surgery. Method of measurement: Number of pads during surgery and amount of bleeding in drain in postoperative pereiod. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of received packed cells. Timepoint: During surgery till 48 hours after surgery. Method of measurement: Number of packed cell. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAhmadreza Mohtadi
Jundishapur University of Medical Sciences
Outcome results
None listed