Recurrent abortion. spontaneous abortion
Conditions
Interventions
Intervention 1: control group: Participants are treated with 400 mg vaginal progesterone suppositories (manufactured by Behvazan Pharmaceutical company, Iran) at a dose of 400 mg/day until the 20th we
Treatment - Drugs
control group: Participants are treated with 400 mg vaginal progesterone suppositories (manufactured by Behvazan Pharmaceutical company, Iran) at a dose of 400 mg/day until the 20th week of pregnancy.
control group: Participants are treated with vaginal progesterone suppositories at a dose of 400 mg/day manufactured by Behvazan Pharmaceutical company, Iran, and vitamin D3 at a dose of 4000 IU/day (
Sponsors
Vice Chancellor for research, Kashan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Incidence of 3 or more consecutive recurrent abortions or 2 or more non consecutive abortions; Age less than 35 years and above 18 years; The absence of any known causes of abortion; Pregnancies from one single husband in previous and current abortions Exclusion criteria: Uterine anomalies; The history of allergy on the consumption of progesterone and multivitamins containing vitamin D3; initial abnormal tests of thyroid abnormalities, prolactin, antiphospholipid antibody syndrome and thrombophilia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Continuation of pregnancy beyond 20 weeks of pregnancy in women with recurrent abortion. Timepoint: 20 weeks after the first day of last menstural period. Method of measurement: clinical, laboratory and sonographic findings. | — |
Secondary
| Measure | Time frame |
|---|---|
| Continuation of pregnancy. Timepoint: after pregnancy termination. Method of measurement: after pregnancy termination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzaneh Amini
Department of Obstetrics and Gynecology, Kashan Medical School
Outcome results
None listed