Periimplantitis. Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
Conditions
Interventions
Intervention 1: Control group: Mechanical debridement using ultrasonic scaler and air-powder air polishing device. Intervention 2: Intervention: Two weeks after mechanical debridement, a one mg of mi
Treatment - Devices
Treatment - Drugs
Control group: Mechanical debridement using ultrasonic scaler and air-powder air polishing device.
Intervention: Two weeks after mechanical debridement, a one mg of minocycline hydrochloride microspheres introduced subgingivally into the affected sites.
Sponsors
Vice Chancellor for research of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1) Adults aged 18 or over with at least one implant in function for more than one year 2) Mild peri-imlant inflammatory diseases. defined as: presence of Bleeding on Probing, radio-graphic bon loss at the site of the implant less than 2 mm and probing depth more than 4 mm Exclusion criteria: 1) Any related systemic diseases 2) Smoking 3) Pregnancy and lactation 4) Active periodontal disease 5) Consumption of systemic antibiotics in the late 3 months 6) Need for bacterial prophylaxis with systemic antibiotics 7) Long-term use of any drug affects periodontal tissue conditions 8) Probing depth greater than 6 mm at base line visit 9) Drug and alcohol abuse 10) Uncontrolled diabetes 11) Probing depth less than 4 mm at base line visit
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding on probing (BOP). Timepoint: Baseline, 2 week and 3 month later. Method of measurement: Periodontal Probe. | — |
Secondary
| Measure | Time frame |
|---|---|
| Peri implant probing depth. Timepoint: Baseline, after 2 weeks, after 3 month. Method of measurement: Periodontal prob.;Cytokines level in gingival crevicular fluid (GCF): IL-6, IL-17. Timepoint: Baseline, 2 week and 3 month later. Method of measurement: ELISA test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Pourabbas
Tabriz University of Medical Sciences
Outcome results
None listed