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The efficacy of Rosa damascenes extract in treatment of sexual dysfunction induced by Selective Serotonin Reuptale Inhibitors in women with Major Depressive Disorder

The efficacy of use and without use of Rosa damascenes extract in treatment of sexual dysfunction induced by Selective Serotonin Reuptale Inhibitors in women with Major Depressive Disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013100114333N9
Enrollment
50
Registered
2013-10-18
Start date
2013-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction. Sexual dysfunction, not caused by organic disorder or disease

Interventions

Intervention 1: The intervention group received 3cc Rosa damascenes dropdaily for 8 weeks which was equivalent to17mg citronellol. Intervention 2: The control group received 3cc distilled water (place
Treatment - Drugs
Placebo
The intervention group received 3cc Rosa damascenes dropdaily for 8 weeks which was equivalent to17mg citronellol

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with major depressive disorders according toDSM IV; those who had been treated with a fixed dose of serotonin reup take in hibitors for at least eight weeks. Exclusion criteria: presence of sexual dysfunction before taking serotonin reup take inhibitors; presence of anysystemic or psychiatric disorders , Thyroid disease and hyperprolactinemia or taking any medication which affects sexual activity; anyhistory of drug or alcohol use during 6 recent months; those who have recently had significant changes in sexual activity due to pregnancy, remarriage and divorce

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Libido. Timepoint: At the beginning, 4th and 8th week of the study. Method of measurement: Asking the patient.;Levels of sexual arousal. Timepoint: At the beginning, 4th and 8th week of the study. Method of measurement: Asking the patient.;Orgasmic disorders. Timepoint: At the beginning, 4th and 8th week of the study. Method of measurement: Asking the patient.;Sexual pain disorders. Timepoint: At the beginning, 4th and 8th week of the study. Method of measurement: Asking the patient.;Sexual Satisfaction. Timepoint: At the beginning, 4th and 8th week of the study. Method of measurement: Asking the patient.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026