level of pressure support ventilation on success of extubation in preterm neonates

Comparison of two level of pressure support ventilation on success of extubation in preterm neonates

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201309302801N3

Enrollment

Registered

2014-06-20

Start date

2013-11-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extubation failure. Respiratory failure of newborn

Interventions

Intervention2: Extubation from mechanichal ventilator while neonates receive 6 CmH2O of Pressure in Pressure Support mode

Intervention 1: Intervention 1:Extubation from mechanichal ventilator while neonates receive 10 CmH2O of Pressure in Pressure Support mode/. Intervention 2: Intervention2: Extubation from mechanichal

Treatment - Devices

Intervention 1:Extubation from mechanichal ventilator while neonates receive 10 CmH2O of Pressure in Pressure Support mode/

Eligibility

Sex/Gender

All

Age

1 Days to 1 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all neonates 27-37 weeks gestation; under mechanical ventilation at least 48 hours due to RDS; is in Weaning Phase. Exclusion Criteria: Pneumothorax; congenital anomalies; meconium aspiration pneumonia; congenital heart disease;asphyxia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Extubation failure. Timepoint: 48 hours after intervention. Method of measurement: observation.	—

Secondary

Measure	Time frame
Death. Timepoint: 72 hours after extubation. Method of measurement: observation.;Pneomotorax. Timepoint: 72 hours after extubation. Method of measurement: observation.;Weaning time. Timepoint: from biginning of PSV mode till extubation point. Method of measurement: observation & documentation.;Tidal volume. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.;Work of breathing. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.;Dynamic compliance. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.	—

Measure

Time frame

Death. Timepoint: 72 hours after extubation. Method of measurement: observation.;Pneomotorax. Timepoint: 72 hours after extubation. Method of measurement: observation.;Weaning time. Timepoint: from biginning of PSV mode till extubation point. Method of measurement: observation & documentation.;Tidal volume. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.;Work of breathing. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.;Dynamic compliance. Timepoint: 3 times during PSV mode till extubation. Method of measurement: internal measurement by ventilator device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRoya Farhadi

Mazandaran University Of Medical Sciences

dr.royafarhadi@gmail.com+98 15122330114

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026