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Assessment of Magnesium sulphate and ondansetronon on propofol 2% injection pain

Comparing therapeutic impacts of Magnesium sulphate and ondansetronon on propofol 2% injection pain in general anesthesia in patients undergoing vitrectomy operation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013092613182N3
Enrollment
90
Registered
2013-11-10
Start date
2012-08-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Propofol injection pain. Other and unspecified general anaesthetics

Interventions

Intervention 1: patients in ondansetron group: received four milligrams ondansetron. Intervention 2: Patients in magnesium sulfate group: received 150 mg magnesium sulfate. Intervention 3: patients in
Prevention
Treatment - Drugs
Placebo
patients in ondansetron group: received four milligrams ondansetron
Patients in magnesium sulfate group: received 150 mg magnesium sulfate
patients in placebo group: 3 milliliter normal saline 0.9%

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion:patients undergoing vitrectomy operation using general anesthesia with American Society of Anesthesiologists physical status I and II. Exclusion: known sensitivity to propofol or ondansetron; receiving analgesic or sedative medication in the last 24 hours; presence of infection on the dorsum of the left hand; indications for rapid sequence intubation; presence of cardiac conduction defects; epilepsy; and use of antiarrhythmic medications, thin dorsal veins, renal and liver diseases, neuro-muscular diseases, pregnant women, and uncooperative patients were excluded

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Propofol injection pain. Timepoint: 5, 10, 20 and 25 seconds after trial intervention. Method of measurement: with 4 points scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Amir Bahrami-Ahmadi

Iran University of Medical Sciences

bahramia@gmail.com+98 21 8862 2682

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026