the Effect of Adding Dexmedetumidine to Rupivacaine and Markain on the Pain and Shivering of patients

Comparison of the Effect of Adding Dexmedetumidine to Rupivacaine and Markain on the Pain and Shivering of patients undergoing orthopedic surgery of the lower limb

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130926014779N6

Enrollment

Registered

2020-08-17

Start date

2019-12-31

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain and chills in lower limb orthopedic patients. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group1 :received 15 mg bupivacaine + 5 µg dex methomedin intrathecally. Intervention 2: Intervention group2: received 15 mg of ropivacaine + 5 micrograms of dexamethasone

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Having hemodynamic stability ASA (Class 1 and 2 were considered as inclusion criteria)

Exclusion criteria

Exclusion criteria: History of cardiovascular disease Shortness of breath Diabetes Kidney or liver disease

Design outcomes

Primary

Measure	Time frame
The pain. Timepoint: Before the spinal, after the spinal and during the change of position of the patient and then every 15 minutes to the first hour and also during the entry into recovery and when leaving the recovery and finally three and six hours after the operation. Method of measurement: pain assessment ruler.;Shivering. Timepoint: Before the spinal, after the spinal and during the change of position of the patient and then every 15 minutes to the first hour and also during the entry into recovery and when leaving the recovery and finally three and six hours after the operation. Method of measurement: Shivering scale.	—

Measure

Time frame

The pain. Timepoint: Before the spinal, after the spinal and during the change of position of the patient and then every 15 minutes to the first hour and also during the entry into recovery and when leaving the recovery and finally three and six hours after the operation. Method of measurement: pain assessment ruler.;Shivering. Timepoint: Before the spinal, after the spinal and during the change of position of the patient and then every 15 minutes to the first hour and also during the entry into recovery and when leaving the recovery and finally three and six hours after the operation. Method of measurement: Shivering scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Hashemi

Jahrom University of Medical Sciences

s.f.hashemi7074@gmail.com+98 71 2536 5231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026