Coronary artery disease. Atherosclerotic heart disease
Conditions
Interventions
Intervention 1: Intervention of this research is a ventilation mode is called Airway Pressure Release Ventilation that applied through ventilator and tracheal tube for half an hour. this mode is a inv
Intervention of this research is a ventilation mode is called Airway Pressure Release Ventilation that applied through ventilator and tracheal tube for half an hour. this mode is a inverse ratio mode
This study is a cross-over study and no control group. Intervention (APRV mode) compared with SIMV mode. synchronized intermittent mandatory ventilation is a usual mode of mechanical ventilation in re
Sponsors
Mashhad University of Medical Sciencse- research assisstance
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 40-70 years old; hemodynamic stability in the first visit; EF = 40% ; RASS = -2 to -3; surgery OFF PUMP; CABG without repair or replace the valve; failure to perform CPR during surgery or before the study; failure to perform emergency surgery (out of routine preoperative); absence of underlying lung disease; lack of oxygenation and ventilation disorder; having hypertension before surgery. Exclusion criteria: CPR performed during study; the need to replace volume; -2< RASS <-3; bleeding more than 100ml / hr of Drains; need to have surgery again; pH arterial <7.25; dysrhythmia that lead to the development of hemodynamic changes.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac index. Timepoint: before intervention, half an hour after intervention & half an hour after return to base mode. Method of measurement: lit/min/BSA.;Stroke volume index. Timepoint: before intervention, half an hour after intervention & half an hour after return to base mode. Method of measurement: mi/BSA.;Mean arterial pressure. Timepoint: before intervention, half an hour after intervention & half an hour after return to base mode. Method of measurement: mmHg.;Systemic vascular resistance. Timepoint: before intervention, half an hour after intervention & half an hour after return to base mode. Method of measurement: Dynes?/?sec?/?cm5?. | — |
Secondary
| Measure | Time frame |
|---|---|
| Arterial oxygen saturation. Timepoint: before intervention, half an hour after intervention & half an hour after return to basic mode. Method of measurement: percent.;Ratio ofl arterial oxygen to inspired oxygen fraction. Timepoint: before intervention, half an hour after intervention & half an hour after return to basic mode. Method of measurement: number.;Pressure of arterial co2. Timepoint: before intervention, half an hour after intervention & half an hour after return to basic mode. Method of measurement: mmHg.;Pressure of arterial oxygen. Timepoint: before intervention, half an hour after intervention & half an hour after return to basic mode. Method of measurement: mmHg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactJavad Malekzadeh
Mashhad University of Medical Sciences
Outcome results
None listed