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Acarbose effect in metabolic syndrome

Assessment of the effect of Acarbose on anthropometric indices and metabolic markers in obese women whit metabolic syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130924014752N5
Enrollment
80
Registered
2018-03-05
Start date
2017-03-01
Completion date
Unknown
Last updated
2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Overweight and obesity

Interventions

Intervention 1: Intervention group: acarbose is administrated for three month with 300 mg .At first it is prescribed with low dose 25 mg three times a day,and gradually placebo dose is increased ti

Sponsors

Endocine Research Center of Isfahan University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: BMI=30 or more than 30 Affected by metabolic syndrome Female Age between 20_50 years

Exclusion criteria

Exclusion criteria: Chronic disease beside metabolic syndrome Non cooperative Consuming anti Lipid drugs Consuming Metformin in past year Weight loss or diet in past year

Design outcomes

Primary

MeasureTime frame
Body weight. Timepoint: At the first visit and each two weeks after three month of consumption of total dose of drug or dose of patient tolerance. Method of measurement: Body weight scales.;Height. Timepoint: At first visit and last visit. Method of measurement: Height gauge.;Waist. Timepoint: At first visit and last visit. Method of measurement: Strip meter.;Fasting blood suger. Timepoint: At first visit and end of study. Method of measurement: Enzymatic lab study.;Insulin level of serum. Timepoint: At first visit and end of study. Method of measurement: ELISA method.;Epicardial fat thickness. Timepoint: At first visit and end of study. Method of measurement: Echocardiography.;Body Mass Index (BMI). Timepoint: At first visit and end of study. Method of measurement: BMI = kg/m2 person's weight in kilograms and m2 is their height in metres squared.

Secondary

MeasureTime frame
Flatulence. Timepoint: Each two weeks. Method of measurement: Questioner.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Noushin Khalili

Esfahan University of Medical Sciences

n_khalili@med.mui.ac.ir+98 31 3335 9090

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026