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Affect of Achillea millefolium in Prophylaxis of oral mucositis

Affect of Achillea millefolium in Prophylaxis of oral mucositis induced by chemotherapy in AML patients.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201309215704N2
Enrollment
18
Registered
2014-04-12
Start date
2013-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: Intervention group will receive hospital's routine prophylactic therapy, which is cholorhexidine mouthwash, and Achillea's extract mouthwash. After preparation of Achillea's extractio
Treatment - Drugs
Intervention group will receive hospital's routine prophylactic therapy, which is cholorhexidine mouthwash, and Achillea's extract mouthwash. After preparation of Achillea's extraction, it is used fo
Control group will receive hospital's routine prophylactic therapy, which is cholorhexidine mouthwash. 5 ml Cholorhexidine mouthwash will be used once daily. Patients will be asked not to eat, drink

Sponsors

Hematology and Oncology Research Center, Tabriz University of Medical Sciences, Iran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: AML patients including both male or female ones, aged between 16-85 who are candidate for chemotherapy; Exclusion criteria: Pregnancy; Patients who are not volunteer; Patients with less than 3 weeks duration of hospitalization; Patients with mucositis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Duration of mucositis. Timepoint: From begining of chemotherapy until 21 days later. Method of measurement: Counting number of days.;Severity of mucositis. Timepoint: First day of chemotherapy until 21 days later. Method of measurement: WHO oral mucositis scale.

Secondary

MeasureTime frame
Amount of analgesics requested for pain caused by mouth sores. Timepoint: First day of chemotherapy until 21 days later. Method of measurement: Type and dosage of analgesics recorded in patients records in 21 days duration.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Mashayekhi

Tabriz University of Medical Sciences

mashayekhis@tbzmed.ac.ir+98 41 1339 2593

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026