Post dural puncture headach. Spinal and epidural anaesthesia-induced headache during pregnancy
Conditions
Interventions
Intervention 1: In the group O, before spinal anesthesia , parturients will be received intravenous (i.v) ondansetron 0.15 mg/kg diluted in 5 ml of normal saline . Intervention 2: In the control group
Treatment - Drugs
In the group O, before spinal anesthesia , parturients will be received intravenous (i.v) ondansetron 0.15 mg/kg diluted in 5 ml of normal saline .
In the control group parturients will be received 5 ml ormal saline before spinal anesthesia.
Sponsors
Vice-Chancellery of Research and Technology
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclision Criteria: parturients who will candidate for elective cesarean section under spinal anesthesia . Exclusion criteria: parturients with the history of cardiovascular disorder; taking antimigraine medications or selective serotonin reuptake inhibitors; hypersensitivity to ondansetron and local anesthetic drugs; those who have contraindication to do spinal anesthesia .
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postdural puncture headach. Timepoint: 1st day postoperation, 2nd day post operation, 3rd day postoperation. Method of measurement: Clinical observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of the nausea and vomiting. Timepoint: During surgery, 1st day postoperation. Method of measurement: Clinical observation.;Blood pressure and hear rate. Timepoint: Every 15 minutes during surgery. Method of measurement: Blood pressure: by sphygmomanomete, Heart rate : by electrocardiogram. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Ali Sahmeddini
Shiraz University Of Medical Sciences
Outcome results
None listed