The effect of omega-3 versus placebo on acne in patients aged 13-50 years

The effect of omega-3 versus placebo on acne in patients aged 13-50 years: a triple blinded randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013091714690N1

Enrollment

Registered

2014-02-26

Start date

2012-09-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne. Acne

Interventions

Intervention 1: Oral doxycycline 100 mg daily plus oral 1000 mg omega-3, daily, for 12 weeks. Intervention 2: Oral doxycycline 100 mg daily plus oral placebo including starch, daily, for 12 weeks.

Treatment - Drugs

Placebo

Oral doxycycline 100 mg daily plus oral 1000 mg omega-3, daily, for 12 weeks.

Oral doxycycline 100 mg daily plus oral placebo including starch, daily, for 12 weeks

Eligibility

Sex/Gender

All

Age

13 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: having moderate to severe facial acne vulgaris. Exclusion criteria: (a) being immunodeficient; (b) contraindication of acne treatment; (c) using medications which have interaction with omega-3.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The severity of acne. Timepoint: at the end of sixth and twelfth weeks. Method of measurement: based on global acne grading system.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hassan Faghani

Department of Dermatology

dr.faghani@yahoo.com+98 81 1838 0717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026