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Evaluation of Therapeutic Effect of Descurainia sophia on the patients with hyperthyroidism

Evaluation of Therapeutic Effect of glucoseinolate extract of Descurainia sophia (L.) Webb ex Prantl on the improvement of patients with hyperthyroidism who are treated with methimazole;Pilot study Double Blinded and Placebo-Controlled Clinical Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130911014630N6
Enrollment
16
Registered
2019-08-26
Start date
2019-05-24
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperthyroidism. Thyrotoxicosis, unspecified

Interventions

Intervention 1: Intervention group: methimazole with a dose of 10 to 20 mg per day plus a capsules containing 350 mg of extract of the plant during 3months. Intervention 2: Control group: methimazole

Sponsors

Sari University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between twenty to sixty years Patients with a higher level of FT4 hormones have a parity of 17 pg /L Patients with a FT3 serum level Larger than equal to 5.7 pg/ml Patients with a lower serum TSH level equal to MU / I0.4

Exclusion criteria

Exclusion criteria: Patients with a history of underlying illness, such as diabetes or hypertension or liver failure, such as cirrhosis of the liver and kidney or heart disease, according to patients referenced Use other medications Use cigarettes right now Alcoholism Pregnant patients Lactating patients Patients who have taken an antithyroid drug for the last three months Patient with ALT levels are twice the normal range Patients who are required to receive other medications for the treatment of other illness during the study Patients who experience side effects such as itching or headache or allergies to the drug Requesting a patient or his family to leave the study

Design outcomes

Primary

MeasureTime frame
Level of thyroid hormones. Timepoint: First of the study (before the intervention) and 30, 60 and 90 days after the start of the capsule. Method of measurement: Collection of questionnaires and laboratory tests and periodic clinical examinations.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Farzameh

Sari University of Medical Sciences

atena.farzameh1997@gmail.com.

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026