The effect of Fluoxetine and Cognitive- Behavior Therapy on sexual function

The effect of pharmacotherapy with Fluoxetine and Cognitive- Behavior Therapy on sexual function of females with Obsessive-Compulsive Disorder

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013091014619N1

Enrollment

Registered

2015-05-19

Start date

2013-09-11

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual dysfunction, Obsessive- compulsive disorder. Sexual dysfunction, not caused by organic disorder or disease, Obsessive-compulsive disorder

Interventions

Intervention 1: Drug intervention: 60 mg capsule Fluoxetine daily (twice daily) for 3 months. Intervention 2: Nondrug intervention group: Cognitive- Behavior Therapy done by clinical psychologist duri

Treatment - Drugs

Behavior

Drug intervention: 60 mg capsule Fluoxetine daily (twice daily) for 3 months.

Nondrug intervention group: Cognitive- Behavior Therapy done by clinical psychologist during 10 forty five minutes sessions weekly.

Eligibility

Sex/Gender

Female

Age

18 Years to 52 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 18-52 years old married female patients with Obsessive-Compulsive Disorder according to DSM IV-TR criteria Exclusion criteria: Comorbid axis I and axis II disorders according to clinical interview; psychotic symptoms; past history of sexual dysfunction before recent episode; endocrine disorders (thyroid dysfunction and Diabetes Mellitus); local genitalia problems (vaginitis, pelvic infections); hypogonadism; cardiovascular disorders (angina, Myocardial Infarction); renal dysfunction; neurologic disorders (Cerebrovascular accident, spinal injuries, autonomic pelvic neuropathy); history of abdominal and pelvic surgeries causing sexual dysfunction (oophorectomy, surgery for prolaps); psychiatric drug reception during last month; using other drug causing sexual dysfunction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Kind and severity of obsessions and compulsions. Timepoint: Before the onset of intervention, three months after the onset of intervention. Method of measurement: Obsessive- Compulsive Yale Brown Scale.	—

Secondary

Measure	Time frame
Sexual function. Timepoint: Before the onset of intervention,three months after the onset of intervention. Method of measurement: Female Sexual Function Index.;Sexual satisfaction. Timepoint: Before the onset of intervention, three months after the onset of intervention. Method of measurement: Sexual Satisfaction Scale.;Marital satisfaction. Timepoint: Before the onset of intervention,three months after the onset of intervention. Method of measurement: Marital Satisfaction of Enrich Scale.	—

Measure

Time frame

Sexual function. Timepoint: Before the onset of intervention,three months after the onset of intervention. Method of measurement: Female Sexual Function Index.;Sexual satisfaction. Timepoint: Before the onset of intervention, three months after the onset of intervention. Method of measurement: Sexual Satisfaction Scale.;Marital satisfaction. Timepoint: Before the onset of intervention,three months after the onset of intervention. Method of measurement: Marital Satisfaction of Enrich Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fatemeh Assarian

Kashan University of Medical Sciences

fa_assar@yahoo.com+31 55549111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Mar 11, 2026