Effect of Matricaria chamomilla and Trachyspermum Copticum on Addiction

Comparison Effect of Matricaria chamomilla and Trachyspermum Copticum on Withdrawal Syndrome in Narcotics Anonymous

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201309053227N4

Enrollment

135

Registered

2015-08-19

Start date

2013-08-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Opium Addiction. Mental and behavioural disorders due to use of opioids

Interventions

Intervention 1: Intervention group 1: will take Matricaria chamomilla 20% (oral drops)3cc, TDS, one hours post parandial for one month. Intervention 2: in intervention group 2 patients will receive Tr

Treatment - Drugs

Intervention group 1: will take Matricaria chamomilla 20% (oral drops)3cc, TDS, one hours post parandial for one month

in intervention group 2 patients will receive Trachyspermum copticum10%(oral drops), 3cc, TDS for one month

In control group will take tab clonidin 2 mg per day with in a period one month.

Eligibility

Sex/Gender

Male

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 to 100 years, having opium addiction, man. Exclusion criteria: known underlying disease (physical and mental); Mental retardation; taking other pain medication or herbs in order to reduce symptoms, patients taking methadone,having allergy to drug plants

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Resting Pulse Rate. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;GI Upset. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Sweating. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Tremor. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Restlessness. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Yawning. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Pupil size. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Anxiety or irritability. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Bone or joint aches. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Gooseflesh skin. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Runny nose or tearing. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.	—

Measure

Time frame

Resting Pulse Rate. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;GI Upset. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Sweating. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Tremor. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Restlessness. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Yawning. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Pupil size. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Anxiety or irritability. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Bone or joint aches. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Gooseflesh skin. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.;Runny nose or tearing. Timepoint: 2,5,12,19,26 days. Method of measurement: clinical opiate withdrawal scale.

—

Secondary

Measure	Time frame
-. Timepoint: -. Method of measurement: -.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAshraf Salehi

Arak University Of Medical Science

najm54@yahoo.com+98 86 4622 4143

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026