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Comparative efficacy of fractional laser and clobetasole in Alopecia areata

Comparative efficacy of fractional CO2 laser and topical clobetasole versus topical clobetasole in treatment of patients with alopecia areata

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201309041159N11
Enrollment
10
Registered
2013-10-20
Start date
2012-08-18
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia areata (ophiasis). Ophiasis alopecia areata

Interventions

Intervention 1: A half of treatment site will be used 0.05% clobetasole lotion (Darou pakhsh company) 2 times a day until complete improvement or 12 weeks. Intervention 2: Another half of treatment si
Treatment - Drugs
A half of treatment site will be used 0.05% clobetasole lotion (Darou pakhsh company) 2 times a day until complete improvement or 12 weeks
Another half of treatment site will be treated with fractional co2 laser (Dosis company) with power: 15, Pixel pitch: 1, Dot cycle: 3 and 1 pass, every 2 weeks for 4-6 times and then use of topical 0.

Sponsors

Vice chancellor for research, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria:1- Severity of alopecia less than of head 2- No sensitivity to corticosteroid 3- No bacterial infection on treatment site 4- No pregnancy or breast-feeding 5- Adult patients above 15 years old that do not willing to inject corticosteroid. Exclusion Criteria: Patients who will not return for follow up visits or are not willing to participate will be excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hair re-growth rate. Timepoint: Before intervention and every month after intervention until 3 months. Method of measurement: Point semiquantitative scoring (RGS-5) and Trichoscan device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElaheh Haftbaradaran

Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Ir

elahe_MD2003@YAHOO.COM+98 31 1337 3736

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026