Soy and cardiovascular risk factors

The effect of soy bean consumption on serum lipid profiles and blood pressure on students and members of Isfahan University of Medical sciences aged 18-45

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2013090314551N1

Enrollment

Registered

2013-12-11

Start date

2007-09-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Obesity. Condition 2: blood pressure. Condition 3: lipid profile. Obesity due to excess calories Essential (primary) hypertension Disorders of lipoprotein metabolism and other lipidaemias

Interventions

Intervention 1: intervention group: subjects were recommended to follow their usual diet and physical activity. moreover, they were suggested to intake 75 gr soy bean daily. Intervention 2: Control gr

intervention group: subjects were recommended to follow their usual diet and physical activity. moreover, they were suggested to intake 75 gr soy bean daily.

Control group: subjects were recommended to follow their usual diet and physical activity. no other intervention was implemented.

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Aged 18-45; no special medication use; no dietary supplementation use; be healthy; diastolic blood pressure and systolic blood pressure were 60-80 and 100-13, respectively; no compliance to a specific diet and no smoking. Exclusion criteria: failure to complete or timely use of soybeans during the intervention period; reluctance to cooperate and necessity use of medication during the intervention period

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Decreasing in total cholestrol, triglyceride,VLDL-C, LDL-C and blood pressure levels and increasing in HDL-C levels. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: total cholestrol, triglyceride, VLDL-C and HDL-C levels are measured enzymatically by using standard kits with autoanalyzer, LDL-C levels are calculated by using the Friedewald equation, blood pressure is measured by using a standard sphygmomanometer.	—

Measure

Time frame

Decreasing in total cholestrol, triglyceride,VLDL-C, LDL-C and blood pressure levels and increasing in HDL-C levels. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: total cholestrol, triglyceride, VLDL-C and HDL-C levels are measured enzymatically by using standard kits with autoanalyzer, LDL-C levels are calculated by using the Friedewald equation, blood pressure is measured by using a standard sphygmomanometer.

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Primary

Measure	Time frame
High density lipoprotein. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Low density lipoprotein. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Triglyceride. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Total cholesterol. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Weight. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: kg - standard scale.;Height. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: cm - tape.;Waist circumference. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: cm - tape.;Systolic blood pressure. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mmHg - standard sphygmomanometer.;Diastolic blood pressure. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mmHg - standard sphygmomanometer.	—

Measure

Time frame

High density lipoprotein. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Low density lipoprotein. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Triglyceride. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Total cholesterol. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mg/dl - labratory.;Weight. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: kg - standard scale.;Height. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: cm - tape.;Waist circumference. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: cm - tape.;Systolic blood pressure. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mmHg - standard sphygmomanometer.;Diastolic blood pressure. Timepoint: before the intervention and 6 weeks after intervention. Method of measurement: mmHg - standard sphygmomanometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Shayanfar

Isfahan University of Medical Sciences

mehdishayanfar63@gmail.com+98 31 1452 0123

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026