The Effect of DASH Diet on Coagulation Factors, Liver Enzymes, Fibrosis and Steatosis Score and Metabolic Biomarkers in Children with Hemophilia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20130903014551N6

Enrollment

Registered

2020-05-26

Start date

2020-06-06

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia patient. Acquired hemophilia

Interventions

Intervention 1: Intervention group: Get a DASH diet in the form of diet plans written for 10 weeks and explain the program and replacement list for patients for 3 training sessions, get food record on

Eligibility

Sex/Gender

Male

Age

10 Years to 18 Years

Inclusion criteria

Inclusion criteria: The desire to participate in the study Male gender Suffering from hemophilia Age ranges between 10-18 years Do not use antioxidant supplements for 3 months before the intervention Do not use a special diet

Exclusion criteria

Exclusion criteria: Smoking and alcohol consumption Use of antihypertensive drugs, blood sugar and blood lipids Having liver, heart and kidney diseases

Design outcomes

Primary

Measure	Time frame
Prothrombin test. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;ALT ?AST. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Degree of liver fibrosis and steatosis. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Fibrosaccan device.;Fasting blood sugar. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Lipid profiles. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Complete blood count. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Anthropometric measurements. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Body analysis machine.;Systolic and diastolic blood pressure. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Sphygmomanometer.;Weightand height. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Digital scales and tape measure.;Waist circumference. Timepoint: Before and 10 weeks after the intervention. Method of measurement: tape measure.;Hs-CRP. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Interleukin 6. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.	—

Measure

Time frame

Prothrombin test. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;ALT ?AST. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Degree of liver fibrosis and steatosis. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Fibrosaccan device.;Fasting blood sugar. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Lipid profiles. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Complete blood count. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Anthropometric measurements. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Body analysis machine.;Systolic and diastolic blood pressure. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Sphygmomanometer.;Weightand height. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Digital scales and tape measure.;Waist circumference. Timepoint: Before and 10 weeks after the intervention. Method of measurement: tape measure.;Hs-CRP. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.;Interleukin 6. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.

—

Secondary

Measure	Time frame
Vitamin C. Timepoint: Before and 10 weeks after the intervention. Method of measurement: Blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtena Mahdavi

Esfahan University of Medical Sciences

atena.mahdavi2011@yahoo.com+98 31 3673 4658

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 17, 2026