Depressive disorder. Major depressive disorder, single episode
Conditions
Interventions
Intervention 1: Intervention group: Patients in this group will receive flaxseed oil supplementation, 1000 mg, made by Barijessence company twice a day for 10 weeks. Intervention 2: Control group: Pat
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Ages 18 to 45 years old Having Depression confirmed by a Psychiatrist according to DSM-IV criteria and being treated with antidepressant medications Willingness to cooperate in the project
Exclusion criteria
Exclusion criteria: Having cardiovascular disease and hypertension Having kidney, liver, cancer, diabetes and inflammatory diseases Having addiction and taking any drugs, tobacco or alcohol Taking any multivitamin and omega-3 supplements 3 months before the study Having cysts in the breast and ovary or having family history of cysts
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: Before and after intervention. Method of measurement: Beck questionnaire.;Serum level of BDNF. Timepoint: Before and after intervention. Method of measurement: ELISA method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical activity. Timepoint: At the beginning and end of the intervention. Method of measurement: Physical activity record questionnaire.;Dietary intake. Timepoint: At the beginning the intervention, In the fifth week and end of the intervention. Method of measurement: Two day food record. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Seyyed Morteza Safavi
Esfahan University of Medical Sciences
Outcome results
None listed