Chronic Kidney Disease (CKD) Requiring Hemodialysis. Dependence on renal dialysis
Conditions
Interventions
Intervention 1: Intervention group: For 12 weeks, participants will receive one packet of supplements daily containing 3 grams of glutamine, 2 grams of creatine, and 1 gram of dextrose (for flavor imp
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: They must have been under hemodialysis treatment for at least 3 months. They must undergo dialysis at least 3 times a week. They should not be under the supervision of another study. They should not be pregnant or breastfeeding. They should not have other diseases such as cancer, advanced liver disease, bipolar disorder, or heart failure. They should not have taken medications or supplements that affect the dependent variables, such as L-carnitine, protein supplements, albumin vials, or any nutritional supplements that they have started or changed the dosage of in the past month. They should not have enteral or parenteral nutrition. The patients should be 18 years or older. They should not be candidates for kidney transplant surgery.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum albumin. Timepoint: Measurement of serum albumin before the intervention begins and at the end of the twelfth week. Method of measurement: Blood sample and using the Bromocresol Green method.;Fatigue levels. Timepoint: Measurement of fatigue levels before the intervention begins and at the end of the twelfth week. Method of measurement: MFI-20 questionnaire.;Handgrip strength. Timepoint: Measurement of handgrip strength before the intervention begins and at the end of the twelfth week. Method of measurement: Based on the Southampton method using the handgrip device (SH5002 SAEHAN Spring).;Quality of life levels. Timepoint: Measurement of quality of life levels before the intervention begins and at the end of the twelfth week. Method of measurement: Kidney Disease Quality of Life Questionnaire (KDQOL). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Hossein Rouhani
Esfahan University of Medical Sciences
Outcome results
None listed