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Garlic supplementation in patients with diabetic nephropathy

The effect of garlic supplementation on markers of inflammation and oxidative stress in patients with diabetic nephropathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20130903014551N11
Enrollment
60
Registered
2021-12-14
Start date
2021-12-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic nephropathy. Type 2 diabetes mellitus with kidney complications

Interventions

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: Diagnosis of diabetic nephropathy confirmed by a specialist age 25-75 years old being in the age range of 25 to 75 years clinically in stage 3 (eGFR equivalent to 30 to 59) or stage 4 (eGFR equivalent to 15 to 29) chronic kidney disease

Exclusion criteria

Exclusion criteria: not performing hemodialysis or peritoneal dialysis presence of liver, gastrointestinal, stroke and ischemic heart disease (3 months after stroke and ischemic heart disease), pulmonary disease (asthma and COPD), cancer, hypothyroidism and hyperthyroidism, gastric ulcer, infectious especially hepatitis, garlic allergy No pregnancy and lactation not consuming drugs of anticoagulants such as heparin, warfarin, apixaban, uvaroxaban, penicillamine and 3 months after taking antibiotics No history of taking garlic supplements and no special diet in the last 3 months Not smoking

Design outcomes

Primary

MeasureTime frame
Total antioxidant capacity (TAC). Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Super oxide dismutase. Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Malon di aldehyde. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.;(CRP) C-reactive protein. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyed Mohammad Hossein Rouhani

Esfahan University of Medical Sciences

sm_rouhani@nutr.ac.ir+98 31 3792 3183

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026