Diabetic nephropathy. Type 2 diabetes mellitus with kidney complications
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of diabetic nephropathy confirmed by a specialist age 25-75 years old being in the age range of 25 to 75 years clinically in stage 3 (eGFR equivalent to 30 to 59) or stage 4 (eGFR equivalent to 15 to 29) chronic kidney disease
Exclusion criteria
Exclusion criteria: not performing hemodialysis or peritoneal dialysis presence of liver, gastrointestinal, stroke and ischemic heart disease (3 months after stroke and ischemic heart disease), pulmonary disease (asthma and COPD), cancer, hypothyroidism and hyperthyroidism, gastric ulcer, infectious especially hepatitis, garlic allergy No pregnancy and lactation not consuming drugs of anticoagulants such as heparin, warfarin, apixaban, uvaroxaban, penicillamine and 3 months after taking antibiotics No history of taking garlic supplements and no special diet in the last 3 months Not smoking
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total antioxidant capacity (TAC). Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Super oxide dismutase. Timepoint: Beginning of study - week 8. Method of measurement: Biochemical assessment.;Malon di aldehyde. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment.;(CRP) C-reactive protein. Timepoint: Beginning of the study - week 8. Method of measurement: Biochemical assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Esfahan University of Medical Sciences