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Investigation of prophylactic effect of Pregabalin on headache after spinal anesthesia in patients undergoing cesarean

Investigation of prophylactic effect of the use with or without Pregabalin on headache after spinal anesthesia in patients undergoing cesarean

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013090114333N5
Enrollment
100
Registered
2013-09-30
Start date
2013-09-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: puncture Headache after spinal. Condition 2: Spinal anesthesia in cesarean. Other reaction to spinal and lumbar puncture Spinal and epidural anaesthesia-induced headache during pregnancy

Interventions

Intervention 1: Half of the patients are given 300 Pregabalin with 20 ml water 30 minutes before operation. Intervention 2: Half of the patients in the control group are given 30 minutes before surger
Treatment - Drugs
Placebo
Half of the patients are given 300 Pregabalin with 20 ml water 30 minutes before operation
Half of the patients in the control group are given 30 minutes before surgery

Sponsors

Vice Chancellor for Research Affairs, Kermanshha university of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria :patients who have been admitted as an emergency or elective cesarean between 20 and 35 years old with height between 150 to 170 cm. Exclusion Criteria: the patients aren’t included in the first and second class (based on the American Society of Anesthesia classification); not to sign the written consent; to have an underlying disease; to report any acute or chronic headache before spinal puncture; to take pain medication in the last two days; coagulopathy disorders 7); hemodynamic disorders; abscesses and local infection of the soft tissue or skin in the injection site; severe restlessness; brain lesion; severe mental disorders and addictions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Headache. Timepoint: hours and 7 days after surgery. Method of measurement: Visual pain test (mild / moderate / severe).

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026