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Finasteride effect as a treatment for spontaneous retinal edema

Finasteride effect as a treatment for chronic and recurrent central serous Chorioretinopathy(CSC)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013083114530N1
Enrollment
30
Registered
2014-01-31
Start date
2013-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Serous Chorioretinopathy. Separation of retinal layers

Interventions

finasteride 5 mg tablet, 1 tablet per day up to 3 months(intervention group) no control group.
Treatment - Drugs
finasteride 5 mg tablet, 1 tablet per day up to 3 months(intervention group) no control group

Sponsors

Shahid Sadoughi University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Eligibility criteria:patients with chronic CSCR, which was defined in this study as 1) the presence of subretinal fluid, as determined by spectraldomain OCT;2)the subretinal fluid must have been present for at least 3 months or there was a recurrence of subretinal fluid in ipsilateral eye within the past 3 months. exclusion criteria:corticosteroid use,CNV or other ocular disease that disturb the study outcome,pregnant and nursery women

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Best corrected visual acuity. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: Snellen chart.;Central macular thickness. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: spectral domain OCT.;Subretinal fluid volume. Timepoint: by the intervention initiation,15 days,1,2 and 3 months after intervention,3months after discontinuation of intervention. Method of measurement: spectral domain OCT.

Secondary

MeasureTime frame
Adverse effects(decreased libido,impotence,improper ejaculation,postural hypotension,dizziness). Timepoint: 15 days,1,2 and 3 months after intervention. Method of measurement: pation history taking.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahere Rezaee

Shahid Sadoughi University of Medical Science

t.rezaee@yahoo.com+98 35 1822 4000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026