Evaluation of oral saffron extract effect on intraocular pressure in pseduexfoliation glaucoma patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201308298832N2

Enrollment

Registered

2013-09-22

Start date

2013-09-09

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pseudoexfoliation glaucoma. Glaucoma secondary to other eye disorders

Interventions

Intervention 1: Placebo capsules for 30 days then 1 month wash out. Intervention 2: Saffron 30 mg/daily every day for 30 days then 1 month of wash out period.

Treatment - Drugs

Placebo capsules for 30 days then 1 month wash out

Saffron 30 mg/daily every day for 30 days then 1 month of wash out period

Eligibility

Sex/Gender

All

Age

50 Years to 120 Years

Inclusion criteria

Inclusion criteria: inclusion criteria : pseudoexoliation glaucoma controlled with topical timolol bd and dorzolamid tds ; age >50 exclusion criteria: angle closure glaucoma; systemic componding medication

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Intraocular pressure. Timepoint: baseline, 1rst ,7th,21st and 28 day and after one month wash out. Method of measurement: Goldmann tonometry.	—

Secondary

Measure	Time frame
Intraocular pressure. Timepoint: baseline, 1rst third fourth week and after one month wash out. Method of measurement: goldmann tonometery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactohammad Hossein Jabbarpoor Bonyadi

Gonabad University of Medical Sciences

drbonyadi@gmu.ac.i+98 53 3722 6921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026