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Comparison the Effects of Plantago major Aqueous Extract with Cetirizine in Treatment of Acute Urticaria

Comparison the Efficacy of Plantago major Aqueous Extract with Cetirizine in Treatment of Acute Urticaria: a Double-blind, Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013082914519N1
Enrollment
48
Registered
2014-04-25
Start date
2013-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute urticaria. Urticaria, unspecified

Interventions

Intervention 1: The control group was treated with cetirizine syrup (Citirizine Tolid Daro Tehran Company), 5cc per day for 15 days. Intervention 2: the first group received 10% Plantago major aqueous
Treatment - Drugs
The control group was treated with cetirizine syrup (Citirizine Tolid Daro Tehran Company), 5cc per day for 15 days.
the first group received 10% Plantago major aqueous extract, 5cc per day for 15 days

Sponsors

Ancient Medicine Faculty,Vice chancellor for research, Shahid Beheshti University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 10 to 70 years old patients; no history of autoimmune or immunodeficiency disease; negative drug history; willingness to participate in the study Exclusion criteria: received antihistaminic drugs, or combination of corticosteroids a month before the trial; pregnancy; previous allergy to Antihistamines or any of the ingredients in the herbal medicinal products; unwillingness to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Amount of itching, drug resistance, and side effects. Timepoint: days 3 and 15. Method of measurement: visiting a dermatologist at the clinic.;Number of urticarial lesions. Timepoint: every day. Method of measurement: Asking the patient.;Amount of itching, drug resistance, and side effects. Timepoint: days 9 and 6. Method of measurement: Asking the patient.;Satisfaction of treatment. Timepoint: At the end of the follow ups. Method of measurement: Asking the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Ali Yazdian

Ancient Medicine Faculty, Shahid Beheshti University of Medical Sciences

yazdian980@gmail.com+98 21 8877 3525

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026