Comparison of platelet rich plasma and fractional Co2 laser on skin rejuvenation in patients with aging

Comparison of platelet rich plasma with fractional Co2 laser and fractional Co2 laser alone on skin rejuvenation in patients with aging

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201308281159N10

Enrollment

Registered

2013-09-22

Start date

2012-12-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Face wrinkles. Other specified disorders of skin and subcutaneous tissue

Interventions

Intervention 1: Treatment of platelet rich plasma (PRP) + fractional Co2 laser: First, patients will be anesthetized with topical Lidocaine-P and then will be treated with Co2 fractional laser (Dosis)

Treatment - Other

Treatment of platelet rich plasma (PRP) + fractional Co2 laser: First, patients will be anesthetized with topical Lidocaine-P and then will be treated with Co2 fractional laser (Dosis) with pixel pitc

Treatment with fractional Co2 laser alone: Patients will be anesthetized with topical Lidocaine-P and then will be treated with Co2 fractional laser (Dosis) with pixel pitch: 1, dot cycle: 3 and power

Eligibility

Sex/Gender

All

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Age 30-50 - Patients with mild to moderate wrinkles according to Glogue scale I-III – No coagulation disorders and use of anti coagulated drugs - No infection in treated site - No fever able diseases – No chronic liver diseases - No pregnancy or breast-feeding. Exclusion Criteria: Patients who will not return for follow up visits or are not willing to participate will be excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Severity of face wrinkles. Timepoint: Before treatment and 1 and 3 months after treatment. Method of measurement: Glogue wrinkle scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElaheh Haftbaradaran

Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Ir

elahe_MD2003@YAHOO.COM+98 31 1337 3736

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026