Hypertensive patients. Essential (primary) hypertension
Conditions
Interventions
Intervention 1: The patients in Intervention group will orally receive 5 ml /day of Nigella Sativa seed oil for 8 weeks in addition to their current treatment regimen. Intervention 2: Control group wi
Treatment - Drugs
The patients in Intervention group will orally receive 5 ml /day of Nigella Sativa seed oil for 8 weeks in addition to their current treatment regimen.
Control group will orally receive 5 ml /day of Sunflower seed oil for 8 weeks in addition to their current treatment regimen. Sunflower seed oil, which is used as a placebo, has no real effect on blo
Sponsors
Vice chancellor for research, Mashhad university of medical sciences
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Hypertensive patients with SBP/DBP = 140/90 mmHg who do not suffer from heart, kidney and liver failure were eligible for inclusion. Exclusion criteria: Patients who smoke and patients who consume antioxidant products aren't enrolled in the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diastolic Blood pressure. Timepoint: During the intervention (every week). Method of measurement: blood pressure manometer.;Systolic Blood pressure. Timepoint: During the intervention (every week). Method of measurement: blood pressure manometer.;Malondialdehyde [MDA] in serum. Timepoint: Before and 8 weeks after intervention. Method of measurement: Spectrophotometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood sugar. Timepoint: Before and 8 weeks after the intervention. Method of measurement: Biochemical test.;Lipid profile. Timepoint: Before and 8 weeks after the intervention. Method of measurement: Biochemical test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZamanzadeh Mansoureh
Mashhad University of Medical Sciences
Outcome results
None listed