major postpartum depression. Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified Puerperal psychosis NO
Conditions
Interventions
Intervention 1: Control group: Using placebo alongside the patient's main drug regimen. Intervention 2: Second intervention group: Tablets containing five mg Crocin (prepared in the Pharmacy faculty o
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Nursing mothers after their delivery up to the passage of six months Nursing mothers in the 18-50 age range Delivery of full-term, healthy, singleton baby Acceptance of completion of the informed consent form after providing the necessary information on the investigation Obtaining of an exact diagnosis of the major depressive disorder using Edinburgh questionnaire by a psychiatrist during a clinical examination
Exclusion criteria
Exclusion criteria: Patients with a history of chronic, systemic diseases Patients with a history of medical disorders such as preeclampsia and diabetes Patients allergic to saffron Smoking cigarettes, drinking alcohol and taking drugs Patients with a history hepatic and renal disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mean score of BDI-II. Timepoint: Every two weeks for12 weeks. Method of measurement: BDI_II Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Monitor of, investigation into and finding evidence for completing probable adverse effects of using Corcus Sativus and Crocin in nursing mothers to add to drug's information in herbal pharmacopeia. Timepoint: Beginning of intervention and end of every months during patient's visit for a period of twelve weeks. Method of measurement: Observation and clinical examination of the patient.;Examining patients' response to the alternative medicine. Timepoint: At the end of intervention. Method of measurement: Assessment of patients' number with fifty percent decrease in average score Beck II questionnaire in comparison with the base line.;Examining patient's remission under treatment. Timepoint: The end of intervention. Method of measurement: Assessment of patients' number with seventy percent decrease in average score Beck II questionnaire in comparison with the base line.;Assessment of the effects of such interfering factors as age, treatment protocol, type of delivery and etc. Timepoint: The end of intervention. Method of measurement: Statistical analysis of collected data with SPSS software.;Investigation on alternative medicine on females' sexual function. Timepoint: Beginning of intervention and end of every months. Method of measurement: FSFI Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZhila Taherzadeh
Mashhad University of Medical Sciences
Outcome results
None listed