Effects of magnesium sulfate in prevention of shivering during spinal anesthesia in cesarean section

Comparison effects of magnesium sulfate and placebo in prevention of shivering during spinal anesthesia in cesarean section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201308254780N4

Enrollment

Registered

2013-09-05

Start date

2012-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal anesthesia. Other complications of spinal and epidural anaesthesia during pregnancy

Interventions

Intervention 1: Intervention group: received 30mg/kg Magnesium sulfate ( dilute it in 50 cc normal saline). Intervention 2: Control group: received 50 cc of normal saline.

Treatment - Drugs

Placebo

Intervention group: received 30mg/kg Magnesium sulfate ( dilute it in 50 cc normal saline)

Control group: received 50 cc of normal saline

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: caesarean section under spinal anesthesia in a Pregnant women with ASA I. Exclusion criteria: ASAII and above; Fever before surgery(T>38) and Hypothermia(T<36.5); Absolute prohibition for spinal anesthesia; Allergy to case study drugs; Thyroid Disease; Parkinson; Raynaud's syndrome; Ischemic heart disease; cerebrovascular disorders; Intraoperative blood transfusion; time of surgery more than 120 minutes; administration of Magnesium; administration of of pethidine; Hypertension; renal disease; history of use of cardiac and Hypertension drug.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Shiver. Timepoint: During opreation every 15 minutes to 120 minutes. Method of measurement: Rate of Crossely & Mahajan.;Temperature. Timepoint: Befor spinal anesthesia and every 15 minutes to 120 minutes during surgery. Method of measurement: Genius 2 Electronic Thermometer.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Every 15 minutes to 120 minutes during surgery. Method of measurement: Non-invasive with Cuff.;Heart rate. Timepoint: Every 15 minutes to 120 minutes during surgery. Method of measurement: monitoring.;Nausea & Vomiting. Timepoint: Every 15 minutes to 120 minutes during surgery. Method of measurement: Observation and question.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Alipour

Mashhad University of Medical Sciences

Alipourm@mums.ac.ir+98 51 1801 2612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026