Thromboembolic Disease. 198
Conditions
Interventions
Intervention 1: Dabigatran group: Dabigatran 150 mg stat and 225 mg per day up to 15 days will be prescribed . Intervention 2: Enoxaparin group:subcutaneous enoxaparin(40 mg)12 hours before surgery a
Treatment - Drugs
Dabigatran group: Dabigatran 150 mg stat and 225 mg per day up to 15 days will be prescribed .
Enoxaparin group:subcutaneous enoxaparin(40 mg)12 hours before surgery and then 40 mg every day up to 15 days will be carrird out
Sponsors
?Soicial Security Insurance Office/ Shariati Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Patients who are candidate for total knee replacement(TKR)in shariati hospital Age more than 18 years patient's content Exclusion criteria:History of: Bleeding disorder, Recent stroke, Major surgery,trauma,Myocardial infarction,Uncontrolled Hypertension in recent 3 months,Liver or GI disease,GI or GU bleeding in recent 6 months,Use of NSAIDs in recent week,active malignancy, Thrombocytopnia,Contrast over sensitivity,Renal failure
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Deep Vein Thrombophelebitis of Legs. Timepoint: 15 days after surgery. Method of measurement: Sonodoppler of Legs' Veins. | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding. Timepoint: Every day up to 15 days and then up 3 months. Method of measurement: Physical Exam. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed