External branch of superior laryngeal nerve and post-thyroidectomy voice performance

Value of identifying external branch of superior laryngeal nerve in post operative voice performance: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201308182389N2

Enrollment

Registered

2013-12-27

Start date

2010-09-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Nontoxic goitre. Condition 2: Malignant neoplasm of thyroid gland. Condition 3: Thyrotoxicosis with diffuse goitre. Condition 4: Thyrotoxicosis with toxic multinodular goitre.

Interventions

Intervention 1: Intervention 1: Thyroidectomy plus exploration of EBSLN. Dissection on the superior thyroid pole will be performed by retracting the thyroid inferiorly and medially. The upper pole is

Treatment - Surgery

Intervention 1: Thyroidectomy plus exploration of EBSLN. Dissection on the superior thyroid pole will be performed by retracting the thyroid inferiorly and medially. The upper pole is mobilized and

Intervention 2: Thyroidectomy without exploration of the nerve. Upper pole dissection will be performed with close ligation of the upper pole vessels on the thyroid gland Without exploration the of

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1.Patients over 18 years old 2.Patients who candidate for thyroidectomy Exclusion criteria: 1-Previous history of neck surgery 2-History of neck radiation therapy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Maintaining of the EBSLN during thyroidectomy. Timepoint: before and six months after intervention. Method of measurement: phone call and clinical examination.	—

Secondary

Measure	Time frame
Post operative RLN (recurrent laryngeal nerve) injury (transient and permanent). Timepoint: 3 weeks to 6 months after surgery. Method of measurement: Electromyography of laryngeal muscles.;Post operative EBSLN injury. Timepoint: 3 weeks to 3 months after surgery. Method of measurement: Electromyography of cricothyroid muscle.;Post operative voice change. Timepoint: 3 weeks to 6 months after surgery. Method of measurement: Interview in person or by phone call.	—

Measure

Time frame

Post operative RLN (recurrent laryngeal nerve) injury (transient and permanent). Timepoint: 3 weeks to 6 months after surgery. Method of measurement: Electromyography of laryngeal muscles.;Post operative EBSLN injury. Timepoint: 3 weeks to 3 months after surgery. Method of measurement: Electromyography of cricothyroid muscle.;Post operative voice change. Timepoint: 3 weeks to 6 months after surgery. Method of measurement: Interview in person or by phone call.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mehdi Asgari

Ahvaz Jundishapur University of Medical Sciences

asgarime@ajums.ac.ir+98 61 1333 3050

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026