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The effect of positive end expiratory pressure on the incidence of pulmonary complications.

Effect of positive end expiratory pressure, five and ten cm H2O on the incidence of pulmonary complications in patients undergoing coronary artery bypass surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2013081714377N1
Enrollment
90
Registered
2013-10-26
Start date
2013-08-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery bypass graft. Ischaemic heart disease (chronic) NOS

Interventions

Intervention 1: If the patient is in control group? from arrival to the Intensivel Care Unit to extubation time he will get the amount of 5 cm H2O of positive end expiratory pressure. Intervention 2:
Prevention
If the patient is in control group? from arrival to the Intensivel Care Unit to extubation time he will get the amount of 5 cm H2O of positive end expiratory pressure.
Patients in intervention group? if hemodynamic status is not disrupted? will get for 4 hours an average of PEEP of 10 cm H2O and until extubation time? PEEP of 5 cm H2O will be received.

Sponsors

Vice chancellor for research Lorestan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria in the study are: 1- patients who are in the 30-80 age range. 2- Lack of ejection fraction (EF) less than 30% in preoperative angiography tab. 3- No history of chronic obstructive airway disease (COPD). 4-No previous history of open heart surgery. 5- No history of broken ribs and a chest tube investments. 6- Their operation is not urgent. 7- The level of consciousness (GCS) of patients is equivalent to fifteen. Exclusion criteria are : 1- Time of aortic clamping more than 100 minutes. 2- Time of heart - lung bypass more than 120 minutes. 3??- Use of intra aortic balloon pump during and after surjery. 4- In case a patient needs ventilation protocol out of our research protocol should be excluded. 5- If a Sick has to be transferred to the operating room (OR) again. 6- If the patient is in intubation over 24 hours.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Bottle chest drainage. Timepoint: When the chest tube take out. Method of measurement: According to the ranking of chest bottle.;Pao2/Fio2 ? o2-sat ? Paco2. Timepoint: Start entering the Intensive Care Unit, one hour, four hours, six hours later, just before tracheal extubation, one hour tafter the tracheal extubation , six hours after the tracheal extubation, and then twelve, twenty-four and forty-eight hours after tracheal extubation. Method of measurement: By arterial blood gas analyzers.

Secondary

MeasureTime frame
Pneumothorax. Timepoint: Early entry into the Intensive Care Unit , one hour after tracheal extubation , and 5-7 days after surgery. Method of measurement: By chest radiography.;Pneumonia. Timepoint: Daily. Method of measurement: 1-The new infiltration in chest x- ray? 2- leukocytosis over twelve thousand ? 3- fever over 38.3° C? 4- purulent sputum.;Atelectasis. Timepoint: Early entry into the Intensive Care Unit , one hour after tracheal extubation , and 5-7 days after surgery. Method of measurement: By chest radiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Moradi

Lorestan University of Medical Sciences

moradi_b90@yahoo.com ; masoodmoradi58@yahoo.com+98 66 1323 9704

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026